Download MendeleyHSF1-DBD crystal structure
Feng, H., Liu, W., Wang, D.C.To be published.
5HDN
Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT
- PDB DOI: https://doi.org/10.2210/pdb5HDN/pdb
- NAKB: 5HDN
- Classification: TRANSCRIPTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli, Homo sapiens
- Mutation(s): No
- Deposited: 2016-01-05 Released: 2017-01-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.68 Å
- R-Value Free: 0.202
- R-Value Work: 0.174
- R-Value Observed: 0.175
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Heat shock factor protein 1 | A, B, E [auth C], F [auth D] | 112 | Homo sapiens | Mutation(s): 0 Gene Names: HSF1, HSTF1 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q00613 (Homo sapiens) Explore Q00613 Go to UniProtKB: Q00613 | |||||
PHAROS: Q00613 GTEx: ENSG00000185122 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q00613 | ||||
Sequence AnnotationsExpand | |||||
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Find similar nucleic acids by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | Organism | Image | |
| DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3') | C [auth E], D [auth F], G, H | 12 | Homo sapiens |  | |
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CIT Query on CIT | I [auth A] | CITRIC ACID C6 H8 O7 KRKNYBCHXYNGOX-UHFFFAOYSA-N |  | ||
| NA Query on NA | J [auth A], K [auth B], L [auth D] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.68 Å
- R-Value Free: 0.202
- R-Value Work: 0.174
- R-Value Observed: 0.175
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 39.415 | α = 90 |
| b = 127.367 | β = 100.55 |
| c = 55.268 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XSCALE | data reduction |
| XDS | data scaling |
| XDS | phasing |
Entry History
Deposition Data
- Released Date: 2017-01-11 Deposition Author(s): Feng, H., Liu, W., Wang, D.C.
Revision History (Full details and data files)
- Version 1.0: 2017-01-11
Type: Initial release - Version 1.1: 2017-09-27
Changes: Data collection - Version 1.2: 2023-11-08
Changes: Data collection, Database references, Refinement description
