Download MendeleyViral protease activation mechanism
Yang, H., Chen, X., Ji, X., Xiong, Y., Yang, K., Wu, C.To be published.
5GXJ
Zika Virus NS2B-NS3 protease
- PDB DOI: https://doi.org/10.2210/pdb5GXJ/pdb
- Classification: HYDROLASE
- Organism(s): Zika virus, synthetic construct
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2016-09-18 Released: 2017-05-03
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.60 Å
- R-Value Free: 0.273
- R-Value Work: 0.224
- R-Value Observed: 0.227
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| FLAVIVIRUS_NS2B,LINKER,Peptidase S7 | 224 | Zika virus, synthetic construct | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for Q32ZE1 (Zika virus) Explore Q32ZE1 Go to UniProtKB: Q32ZE1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q32ZE1 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.60 Å
- R-Value Free: 0.273
- R-Value Work: 0.224
- R-Value Observed: 0.227
- Space Group: P 41 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 55.206 | α = 90 |
| b = 55.206 | β = 90 |
| c = 250.135 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
