Crystal Structure of Raptor Adenovirus 1 Fibre Head and Role of the Beta-Hairpin in Siadenovirus Fibre Head Domains
Nguyen, T.H., Ballmann, M.Z., Do, H.T., Truong, H.N., Benko, M., Harrach, B., van Raaij, M.J.(2016) Virol J 13: 106
- PubMed: 27334597 
- DOI: https://doi.org/10.1186/s12985-016-0558-7
- Primary Citation of Related Structures:  
5FJL, 5FLD - PubMed Abstract: 
Most adenoviruses recognize their host cells via an interaction of their fibre head domains with a primary receptor. The structural framework of adenovirus fibre heads is conserved between the different adenovirus genera for which crystal structures have been determined (Mastadenovirus, Aviadenovirus, Atadenovirus and Siadenovirus), but genus-specific differences have also been observed. The only known siadenovirus fibre head structure, that of turkey adenovirus 3 (TAdV-3), revealed a twisted beta-sandwich resembling the reovirus fibre head architecture more than that of other adenovirus fibre heads, plus a unique beta-hairpin embracing a neighbouring monomer. The TAdV-3 fibre head was shown to bind sialyllactose.
Organizational Affiliation: 
Departamento de Estructura de Macromoléculas, Centro Nacional de Biotecnología (CNB-CSIC), Calle Darwin 3, E-28049, Madrid, Spain.