5EOD
Human Plasma Coagulation FXI with peptide LP2
- PDB DOI: https://doi.org/10.2210/pdb5EOD/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Cricetulus griseus, synthetic construct
- Mutation(s): No 
- Deposited: 2015-11-10 Released: 2016-04-06 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.10 Å
- R-Value Free: 0.274 
- R-Value Work: 0.189 
- R-Value Observed: 0.194 
This is version 1.3 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Coagulation factor XI | 606 | Homo sapiens | Mutation(s): 0  Gene Names: F11 EC: 3.4.21.27 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P03951 (Homo sapiens) Explore P03951  Go to UniProtKB:  P03951 | |||||
PHAROS:  P03951 GTEx:  ENSG00000088926  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P03951 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
LP2 | 6 | Homo sapiens | Mutation(s): 0  | ||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | C [auth A], D [auth A], E [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.10 Å
- R-Value Free: 0.274 
- R-Value Work: 0.189 
- R-Value Observed: 0.194 
- Space Group: P 43 21 2
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 81.065 | α = 90 |
b = 81.065 | β = 90 |
c = 253.084 | γ = 90 |
Software Name | Purpose |
---|---|
REFMAC | refinement |
PHENIX | refinement |
XDS | data reduction |
PHASER | phasing |
Entry History 
Deposition Data
- Released Date: 2016-04-06  Deposition Author(s): Wong, S.S., Ostergaard, S., Hall, G., Li, C., Williams, P.M., Stennicke, H., Emsley, J.
Revision History (Full details and data files)
- Version 1.0: 2016-04-06
Type: Initial release - Version 1.1: 2016-06-22
Changes: Database references - Version 1.2: 2018-10-24
Changes: Advisory, Data collection, Derived calculations - Version 1.3: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Structure summary