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UNINHIBITED MOUSE CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2)
5COX
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Oxidoreductase
    Structure Weight: 274398.11
    Molecule: CYCLOOXYGENASE-2
    Polymer: 1 Type: protein Length: 587
    Chains: A, B, C, D
    EC#: 1.14.99.1   
    Organism: Mus musculus
    Gene Names: Ptgs2 Cox-2 Cox2 Pghs-b Tis10
    UniProtKB: Protein Feature View | Search PDB | Q05769  
    Membrane Protein:   Source: inferred by homology
    MONOTOPIC MEMBRANE PROTEINS
    Cyclooxygenases
    Cyclooxygenase-2
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Mus musculus   Taxonomy   Common Name: House mouse Expression System: Spodoptera frugiperda  
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    HEM
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    HEM C34 H32 Fe N4 O4
    PROTOPORPHYRIN IX CONTAINING FE
    NAG
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    NAG C8 H15 N O6
    N-ACETYL-D-GLUCOSAMINE
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Kurumbail, R.,  Stallings, W.

    Deposition:   1996-12-18
    Release:   1997-12-24
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Version format compliance
    2011-07-13
    Non-polymer description
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    Resolution[Å]:   3.00
    R-Value: 0.321 (obs.)
    R-Free: 0.308
    Space Group: P 21 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 180.46 α = 90.00 
    b = 134.42 β = 90.00 
    c = 119.90 γ = 90.00