Download MendeleySerine/threonine-protein kinase pim-1
Li, W., Wan, X., Huang, N.To be published.
5C1Q
Serine/threonine-protein kinase pim-1
- PDB DOI: https://doi.org/10.2210/pdb5C1Q/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2015-06-15 Released: 2015-12-16
- Funding Organization(s): Chinese Ministry of Science and Technology 973 Grant
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.00 Å
- R-Value Free: 0.246
- R-Value Work: 0.174
- R-Value Observed: 0.178
This is version 1.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Serine/threonine-protein kinase pim-1 | A [auth B] | 289 | Homo sapiens | Mutation(s): 0 Gene Names: PIM1 EC: 2.7.11.1 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P11309 (Homo sapiens) Explore P11309 Go to UniProtKB: P11309 | |||||
PHAROS: P11309 GTEx: ENSG00000137193 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P11309 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 4YK Query on 4YK | B | 3-methoxy[1]benzothieno[2,3-c]quinolin-6(5H)-one C16 H11 N O2 S GPCQYADOLCARPD-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.00 Å
- R-Value Free: 0.246
- R-Value Work: 0.174
- R-Value Observed: 0.178
- Space Group: P 65
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 99.37 | α = 90 |
| b = 99.37 | β = 90 |
| c = 80.68 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DENZO | data scaling |
| PHENIX | phasing |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| Chinese Ministry of Science and Technology 973 Grant | China | 2014CB849802 |
Revision History (Full details and data files)
- Version 1.0: 2015-12-16
Type: Initial release - Version 1.1: 2024-03-20
Changes: Data collection, Database references, Derived calculations
