Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Liu, L.K., Finzel, B.C.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
CD44 antigen | 151 | Mus musculus | Mutation(s): 2  Gene Names: Cd44, Ly-24 | ||
UniProt | |||||
Find proteins for P15379 (Mus musculus) Explore P15379  Go to UniProtKB:  P15379 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P15379 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 2 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
4X1 Query on 4X1 | C [auth A] | 3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine C12 H18 N2 OZWGXKVQFUBMTE-UHFFFAOYSA-N | |||
DMS Query on DMS | B [auth A] | DIMETHYL SULFOXIDE C2 H6 O S IAZDPXIOMUYVGZ-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 30.85 | α = 90 |
b = 81.72 | β = 117.97 |
c = 32.12 | γ = 90 |
Software Name | Purpose |
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XSCALE | data scaling |
PHASER | phasing |
REFMAC | refinement |
PDB_EXTRACT | data extraction |