5X0T

Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.50 Å
  • R-Value Free: 0.300 
  • R-Value Work: 0.246 
  • R-Value Observed: 0.248 

wwPDB Validation   3D Report Full Report


This is version 1.0 of the entry. See complete history


Literature

Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody

Zhang, M.-Y.Lin, P.Zhu, P.Chen, Z.-N.

To be published.

Macromolecules
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Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
6H8 Fab fragment heavy chainA,
B [auth C]
241Mus musculusMutation(s): 0 
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Entity ID: 2
MoleculeChains Sequence LengthOrganismDetailsImage
6H8 Fab fragment light chainC [auth B],
D
234Mus musculusMutation(s): 0 
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Entity ID: 3
MoleculeChains Sequence LengthOrganismDetailsImage
Basigin
E, F
89Homo sapiensMutation(s): 0 
Gene Names: BSGUNQ6505/PRO21383
UniProt & NIH Common Fund Data Resources
Find proteins for P35613 (Homo sapiens)
Explore P35613 
Go to UniProtKB:  P35613
PHAROS:  P35613
GTEx:  ENSG00000172270 
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UniProt GroupP35613
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.50 Å
  • R-Value Free: 0.300 
  • R-Value Work: 0.246 
  • R-Value Observed: 0.248 
  • Space Group: P 1 21 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 46.986α = 90
b = 83.486β = 92.92
c = 130.193γ = 90
Software Package:
Software NamePurpose
PHENIXrefinement
HKL-2000data reduction
HKL-2000data scaling
PHASERphasing

Structure Validation

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Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
National Science and Technology Major ProjectsChina2013ZX09301301
National Basic Research Project(973 Program)China2015CB553701

Revision History  (Full details and data files)

  • Version 1.0: 2018-01-24
    Type: Initial release