Download MendeleyAbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery
Convery, M.A.To be published.
5OBF
fAb. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
- PDB DOI: https://doi.org/10.2210/pdb5OBF/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Mus musculus
- Expression System: Mus musculus
- Mutation(s): No
- Deposited: 2017-06-26 Released: 2017-11-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.92 Å
- R-Value Free: 0.210
- R-Value Work: 0.174
- R-Value Observed: 0.175
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| fAb Heavy chain | A [auth H] | 217 | Mus musculus | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| fAb Light chain | B [auth L] | 217 | Mus musculus | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | C [auth L] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| GOL Query on GOL | D [auth L], E [auth L] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.92 Å
- R-Value Free: 0.210
- R-Value Work: 0.174
- R-Value Observed: 0.175
- Space Group: I 4
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 132.397 | α = 90 |
| b = 132.397 | β = 90 |
| c = 56.914 | γ = 90 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2017-11-08 Deposition Author(s): Vicentini, G., Convery, M.A.
Revision History (Full details and data files)
- Version 1.0: 2017-11-08
Type: Initial release
