Download MendeleyCrystal structure of Thioredoxin 1 from Cryptococcus neoformans at 1.8 Angstroms resolution
Bravo-Chaucanes, C.P., Abadio, A.K.R., Kioshima, E.S., Felipe, M.S.S., Barbosa, J.A.R.G.To be published.
5JY5
Crystal structure of Thioredoxin 1 from Cryptococcus neoformans at 1.8 Angstroms resolution
- PDB DOI: https://doi.org/10.2210/pdb5JY5/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Cryptococcus neoformans var. grubii H99
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2016-05-13 Released: 2017-06-07
- Funding Organization(s): Brazilian National Council for Scientific and Technological Development (CNPq), FAPDF/CNPq
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.195
- R-Value Work: 0.156
- R-Value Observed: 0.158
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Thioredoxin | 110 | Cryptococcus neoformans var. grubii H99 | Mutation(s): 0 Gene Names: CNAG_02801 |  | |
UniProt | |||||
Find proteins for J9VKF2 (Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)) Explore J9VKF2 Go to UniProtKB: J9VKF2 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | J9VKF2 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| TRS Query on TRS | G [auth B] | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL C4 H12 N O3 LENZDBCJOHFCAS-UHFFFAOYSA-O |  | ||
| SO4 Query on SO4 | E [auth A], H [auth B], I [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| GOL Query on GOL | C [auth A], D [auth A], F [auth B] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.195
- R-Value Work: 0.156
- R-Value Observed: 0.158
- Space Group: P 64 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 110.706 | α = 90 |
| b = 110.706 | β = 90 |
| c = 91.763 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2017-06-07 Deposition Author(s): Bravo-Chaucanes, C.P., Abadio, A.K.R., Kioshima, E.S., Felipe, M.S.S., Barbosa, J.A.R.G.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Brazilian National Council for Scientific and Technological Development (CNPq) | Brazil | 564007/2010-2 |
| FAPDF/CNPq | Brazil | 193.000.569/2009 |
Revision History (Full details and data files)
- Version 1.0: 2017-06-07
Type: Initial release - Version 1.1: 2019-04-17
Changes: Author supporting evidence, Data collection - Version 1.2: 2020-01-08
Changes: Author supporting evidence - Version 1.3: 2023-09-27
Changes: Data collection, Database references, Refinement description
