Download MendeleyLipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from unrelated V-genes
Haji-Ghassemi, O., Muller-Loennies, S., Rodriguez, T., Brade, L., Kosma, P., Brade, H., Evans, S.V.(2015) J Biol Chem
5DQJ
Structure of unliganded S55-5 Fab
- PDB DOI: https://doi.org/10.2210/pdb5DQJ/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Mus musculus
- Mutation(s): No
- Deposited: 2015-09-14 Released: 2016-03-09
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.61 Å
- R-Value Free: 0.228
- R-Value Work: 0.193
- R-Value Observed: 0.195
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| S55-5 Fab (IgG1 kappa) light chain | A [auth L], C [auth B] | 218 | Mus musculus | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| S55-5 Fab (IgG1) heavy chain | B [auth H], D [auth A] | 222 | Mus musculus | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.61 Å
- R-Value Free: 0.228
- R-Value Work: 0.193
- R-Value Observed: 0.195
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 53.607 | α = 90 |
| b = 139.872 | β = 110.66 |
| c = 72.076 | γ = 90 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data scaling |
| PHASER | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| HKL-2000 | data reduction |
Entry History
Deposition Data
- Released Date: 2016-03-09 Deposition Author(s): Haji-Ghassemi, O., Evans, S.V.
Revision History (Full details and data files)
- Version 1.0: 2016-03-09
Type: Initial release - Version 1.1: 2023-09-27
Changes: Data collection, Database references, Derived calculations, Refinement description
