5A3I
Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin
- PDB DOI: https://doi.org/10.2210/pdb5A3I/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Influenza A virus (A/Viet Nam/1203/2004(H5N1)), Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No 
- Deposited: 2015-06-01 Released: 2015-07-22 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.89 Å
- R-Value Free: 0.277 
- R-Value Work: 0.244 
- R-Value Observed: 0.245 
This is version 2.1 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
HEMAGGLUTININ | 328 | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | Mutation(s): 0  | ||
UniProt | |||||
Find proteins for Q6DQ33 (Influenza A virus (strain A/Vietnam/1203/2004 H5N1)) Explore Q6DQ33  Go to UniProtKB:  Q6DQ33 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q6DQ33 | ||||
Sequence AnnotationsExpand | |||||
|
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
HEMAGGLUTININ | 166 | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | Mutation(s): 0  | ||
UniProt | |||||
Find proteins for A8UDR1 (Influenza A virus (strain A/Vietnam/1203/2004 H5N1)) Explore A8UDR1  Go to UniProtKB:  A8UDR1 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A8UDR1 | ||||
Sequence AnnotationsExpand | |||||
|
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN | 230 | Homo sapiens | Mutation(s): 0  | ||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
|
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 4 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
ANTI-HAEMAGGLUTININ HA1 FAB LIGHT CHAIN | 219 | Homo sapiens | Mutation(s): 0  | ||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
|
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 5 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
HEMAGGLUTININ | 166 | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | Mutation(s): 0  | ||
UniProt | |||||
Find proteins for A8UDR1 (Influenza A virus (strain A/Vietnam/1203/2004 H5N1)) Explore A8UDR1  Go to UniProtKB:  A8UDR1 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A8UDR1 | ||||
Sequence AnnotationsExpand | |||||
|
Oligosaccharides
Small Molecules
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | K [auth E] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.89 Å
- R-Value Free: 0.277 
- R-Value Work: 0.244 
- R-Value Observed: 0.245 
- Space Group: P 1
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 86.75 | α = 78.67 |
b = 87.7 | β = 84.66 |
c = 100.9 | γ = 73.91 |
Software Name | Purpose |
---|---|
REFMAC | refinement |
XDS | data reduction |
SCALA | data scaling |
PHASER | phasing |
Entry History 
Deposition Data
- Released Date: 2015-07-22  Deposition Author(s): Xiong, X., Corti, D., Liu, J., Pinna, D., Foglierini, M., Calder, L.J., Martin, S.R., Lin, Y.P., Walker, P.A., Collins, P.J., Monne, I., Suguitan Jr, A.L., Santos, C., Temperton, N.J., Subbarao, K., Lanzavecchia, A., Gamblin, S.J., Skehel, J.J.
Revision History (Full details and data files)
- Version 1.0: 2015-07-22
Type: Initial release - Version 1.1: 2015-08-12
Changes: Database references - Version 1.2: 2015-09-09
Changes: Source and taxonomy - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Derived calculations, Other, Structure summary - Version 2.1: 2024-01-10
Changes: Data collection, Database references, Refinement description, Structure summary