4Z54

High Resolution Human Septin3 GTPase domain with alpha-zero helix in complex with GDP


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.83 Å
  • R-Value Free: 0.199 
  • R-Value Work: 0.170 
  • R-Value Observed: 0.171 

wwPDB Validation   3D Report Full Report


Ligand Structure Quality Assessment 


This is version 2.3 of the entry. See complete history


Literature

A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface

Castro, D.K.S.V.da Silva, S.M.O.Pereira, H.M.Macedo, J.N.A.Leonardo, D.A.Valadares, N.F.Kumagai, P.S.Brandao-Neto, J.Araujo, A.P.U.Garratt, R.C.

(2020) IUCrJ 


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Neuronal-specific septin-3
A, B
287Homo sapiensMutation(s): 0 
Gene Names: SEPT3SEP3
UniProt & NIH Common Fund Data Resources
Find proteins for Q9UH03 (Homo sapiens)
Explore Q9UH03 
Go to UniProtKB:  Q9UH03
PHAROS:  Q9UH03
GTEx:  ENSG00000100167 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ9UH03
Sequence Annotations
Expand
  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.83 Å
  • R-Value Free: 0.199 
  • R-Value Work: 0.170 
  • R-Value Observed: 0.171 
  • Space Group: P 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 43.41α = 99.29
b = 44.55β = 100.77
c = 78.95γ = 108.39
Software Package:
Software NamePurpose
xia2data scaling
PHASERphasing
PHENIXrefinement
PDB_EXTRACTdata extraction

Structure Validation

View Full Validation Report



Ligand Structure Quality Assessment 


Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2016-04-06
    Type: Initial release
  • Version 1.1: 2017-11-01
    Changes: Author supporting evidence, Data collection, Derived calculations
  • Version 2.0: 2018-09-19
    Changes: Advisory, Atomic model, Data collection, Database references, Derived calculations, Structure summary
  • Version 2.1: 2020-04-22
    Changes: Database references
  • Version 2.2: 2020-05-13
    Changes: Database references
  • Version 2.3: 2024-03-06
    Changes: Data collection, Database references, Derived calculations