Download MendeleyStructure of a Metallo-beta-lactamase
Ferguson, J.A., Makena, A., Brem, J., McDonough, M.A., Schofield, C.J.To be published.
4TYF
Structure of a Metallo-beta-lactamase
- PDB DOI: https://doi.org/10.2210/pdb4TYF/pdb
- Classification: HYDROLASE
- Organism(s): Escherichia coli
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2014-07-08 Released: 2015-07-15
- Funding Organization(s): Medical Research Council (United Kingdom)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.10 Å
- R-Value Free: 0.173
- R-Value Work: 0.150
- R-Value Observed: 0.151
wwPDB Validation 3D Report Full Report
This is version 2.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| NDM-4 | 231 | Escherichia coli | Mutation(s): 0 Gene Names: blaNDM-4 |  | |
UniProt | |||||
Find proteins for H6WZS9 (Escherichia coli) Explore H6WZS9 Go to UniProtKB: H6WZS9 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | H6WZS9 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN Query on ZN | B [auth A], C [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.10 Å
- R-Value Free: 0.173
- R-Value Work: 0.150
- R-Value Observed: 0.151
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 41.7 | α = 90 |
| b = 59.08 | β = 97.61 |
| c = 42 | γ = 90 |
| Software Name | Purpose |
|---|---|
| XDS | data reduction |
| PHASER | phasing |
| PHENIX | refinement |
| Coot | model building |
Entry History & Funding Information
Deposition Data
- Released Date: 2015-07-15 Deposition Author(s): Ferguson, J.A., Makena, A., Brem, J., McDonough, M.A., Schofield, C.J.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Medical Research Council (United Kingdom) | United Kingdom | G1100135 |
Revision History (Full details and data files)
- Version 1.0: 2015-07-15
Type: Initial release - Version 2.0: 2017-09-13
Changes: Advisory, Atomic model, Author supporting evidence, Data collection, Derived calculations - Version 2.1: 2018-01-31
Changes: Database references - Version 2.2: 2023-12-20
Changes: Data collection, Database references, Refinement description
