Download MendeleyCrystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis
Nasir, N., Anant, A., Vyas, R., Biswal, B.K.To be published.
4R8D
Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis
- PDB DOI: https://doi.org/10.2210/pdb4R8D/pdb
- Classification: TRANSFERASE
- Organism(s): Mycobacterium tuberculosis H37Rv
- Expression System: Mycolicibacterium smegmatis
- Mutation(s): No
- Deposited: 2014-09-01 Released: 2015-09-02
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.05 Å
- R-Value Free: 0.255
- R-Value Work: 0.208
- R-Value Observed: 0.210
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Histidinol-phosphate aminotransferase | 394 | Mycobacterium tuberculosis H37Rv | Mutation(s): 0 Gene Names: hisC, P425_01659, RVBD_1600 EC: 2.6.1.9 |  | |
UniProt | |||||
Find proteins for P9WML7 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WML7 Go to UniProtKB: P9WML7 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P9WML7 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PLP Query on PLP | C [auth A], H [auth B] | PYRIDOXAL-5'-PHOSPHATE C8 H10 N O6 P NGVDGCNFYWLIFO-UHFFFAOYSA-N |  | ||
| MES Query on MES | D [auth A], I [auth B] | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID C6 H13 N O4 S SXGZJKUKBWWHRA-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | E [auth A], F [auth A], G [auth A], J [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.05 Å
- R-Value Free: 0.255
- R-Value Work: 0.208
- R-Value Observed: 0.210
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 67.525 | α = 90 |
| b = 101.523 | β = 90 |
| c = 114.947 | γ = 90 |
| Software Name | Purpose |
|---|---|
| StructureStudio | data collection |
| PHASER | phasing |
| REFMAC | refinement |
| HKL-2000 | data reduction |
| SCALEPACK | data scaling |
Entry History
Deposition Data
- Released Date: 2015-09-02 Deposition Author(s): Nasir, N., Anant, A., Vyas, R., Biswal, B.K.
Revision History (Full details and data files)
- Version 1.0: 2015-09-02
Type: Initial release - Version 1.1: 2023-11-08
Changes: Data collection, Database references, Derived calculations, Refinement description
