4NQJ

Structure of coiled-coil domain

PDB DOI: https://doi.org/10.2210/pdb4NQJ/pdb

Classification: LIGASE
Organism(s): Homo sapiens
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2013-11-25 Released: 2014-05-21
Deposition Author(s): Yang, M., Li, Y.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.15 Å
R-Value Free: 0.251
R-Value Work: 0.216
R-Value Observed: 0.218

wwPDB Validation 3D Report Full Report

Ligand Structure Quality Assessment

This is version 1.2 of the entry. See complete history.

Literature

Structural insights into the TRIM family of ubiquitin E3 ligases.

Li, Y., Wu, H., Wu, W., Zhuo, W., Liu, W., Zhang, Y., Cheng, M., Chen, Y.G., Gao, N., Yu, H., Wang, L., Li, W., Yang, M.

(2014) Cell Res 24: 762-765

PubMed: 24722452 Search on PubMedSearch on PubMed Central
DOI: https://doi.org/10.1038/cr.2014.46
Primary Citation of Related Structures:
4NQJ

Organizational Affiliation

1] MOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China [2] Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.

Macromolecule Content

Total Structure Weight: 65.02 kDa
Atom Count: 4,716
Modelled Residue Count: 530
Deposited Residue Count: 537
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
E3 ubiquitin-protein ligase TRIM69	A, B, C	179	Homo sapiens	Mutation(s): 0 Gene Names: TRIM69 EC: 6.3.2
UniProt & NIH Common Fund Data Resources
Find proteins for Q86WT6 (Homo sapiens) Explore Q86WT6 Go to UniProtKB: Q86WT6
PHAROS: Q86WT6 GTEx: ENSG00000185880
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q86WT6
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
LMT Query on LMT Download Ideal Coordinates CCD File SDF format, chain D [auth A] SDF format, chain E [auth A] SDF format, chain F [auth B] SDF format, chain G [auth C] SDF format, chain H [auth C] MOL2 format, chain D [auth A] MOL2 format, chain E [auth A] MOL2 format, chain F [auth B] MOL2 format, chain G [auth C] MOL2 format, chain H [auth C]	D [auth A], E [auth A], F [auth B], G [auth C], H [auth C]	DODECYL-BETA-D-MALTOSIDE C₂₄ H₄₆ O₁₁ NLEBIOOXCVAHBD-QKMCSOCLSA-N		Interactions Focus chain D [auth A] Focus chain E [auth A] Focus chain F [auth B] Focus chain G [auth C] Focus chain H [auth C] Interactions & Density Focus chain D [auth A] Focus chain E [auth A] Focus chain F [auth B] Focus chain G [auth C] Focus chain H [auth C]