4N33
Structure of langerin CRD complexed with GlcNAc-beta1-3Gal-beta1-4Glc-beta-CH2CH2N3
- PDB DOI: https://doi.org/10.2210/pdb4N33/pdb
- Classification: SUGAR BINDING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2013-10-06 Released: 2013-11-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.85 Å
- R-Value Free: 0.218
- R-Value Work: 0.173
- R-Value Observed: 0.175
wwPDB Validation 3D Report Full Report
This is version 2.1 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| C-type lectin domain family 4 member K | 136 | Homo sapiens | Mutation(s): 1 Gene Names: CD207, CLEC4K |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9UJ71 (Homo sapiens) Explore Q9UJ71 Go to UniProtKB: Q9UJ71 | |||||
PHAROS: Q9UJ71 GTEx: ENSG00000116031 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9UJ71 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CA Query on CA | I [auth A], J [auth B], K [auth C], L [auth D] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.85 Å
- R-Value Free: 0.218
- R-Value Work: 0.173
- R-Value Observed: 0.175
- Space Group: P 42
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 79.42 | α = 90 |
| b = 79.42 | β = 90 |
| c = 91.71 | γ = 90 |
| Software Name | Purpose |
|---|---|
| Blu-Ice | data collection |
| PHENIX | model building |
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHENIX | phasing |
Entry History
Deposition Data
- Released Date: 2013-11-20 Deposition Author(s): Feinberg, H., Rowntree, T.J.W., Tan, S.L.W., Drickamer, K., Weis, W.I., Taylor, M.E.
Revision History (Full details and data files)
- Version 1.0: 2013-11-20
Type: Initial release - Version 1.1: 2013-12-04
Changes: Database references - Version 1.2: 2014-01-22
Changes: Database references - Version 1.3: 2017-11-15
Changes: Refinement description - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2023-09-20
Changes: Data collection, Database references, Refinement description, Structure summary
