JAK1 kinase (JH1 domain) in complex with the inhibitor (TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXYL)ACETONITRILE
4IVC
Primary Citation
 
 
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Eigenbrot, C.,  Shia, S.

    Deposition:   2013-01-22
    Release:   2013-05-22
    Last Modified (REVDAT):   2013-07-03
     
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    2013-07-03
    Citation
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.35
    R-Value: 0.200 (obs.)
    R-Free: 0.263
    Space Group: P 1 21 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 42.33 α = 90.00 
    b = 172.87 β = 94.75 
    c = 44.12 γ = 90.00