JAK2 kinase (JH1 domain) in complex with the inhibitor TRANS-4-[(8AS)-2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(8AH)-YL]CYCLOHEXANECARBONITRILE
4IVA
Primary Citation
 
 
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Eigenbrot, C.,  Shia, S.

    Deposition:   2013-01-22
    Release:   2013-05-22
    Last Modified (REVDAT):   2013-07-03
     
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    2013-07-03
    Citation
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   1.50
    R-Value: 0.176 (obs.)
    R-Free: 0.193
    Space Group: P 1 21 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 44.25 α = 90.00 
    b = 69.30 β = 101.02 
    c = 50.09 γ = 90.00