4GX6
AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Mutation E192Q
- PDB DOI: https://doi.org/10.2210/pdb4GX6/pdb
- Classification: HYDROLASE
- Organism(s): Sus scrofa
- Expression System: Escherichia coli
- Mutation(s): Yes 
- Deposited: 2012-09-03 Released: 2013-09-04 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.273 
- R-Value Work: 0.211 
- R-Value Observed: 0.214 
This is version 1.2 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Fructose-1,6-bisphosphatase 1 | 337 | Sus scrofa | Mutation(s): 1  Gene Names: FBP, FBP1 EC: 3.1.3.11 | ||
UniProt | |||||
Find proteins for P00636 (Sus scrofa) Explore P00636  Go to UniProtKB:  P00636 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P00636 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 4 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
AMP Query on AMP | F [auth A], K [auth B] | ADENOSINE MONOPHOSPHATE C10 H14 N5 O7 P UDMBCSSLTHHNCD-KQYNXXCUSA-N | |||
F6P Query on F6P | C [auth A], H [auth B] | 6-O-phosphono-beta-D-fructofuranose C6 H13 O9 P BGWGXPAPYGQALX-ARQDHWQXSA-N | |||
PO4 Query on PO4 | G [auth A], L [auth B] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K | |||
MG Query on MG | D [auth A], E [auth A], I [auth B], J [auth B] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.273 
- R-Value Work: 0.211 
- R-Value Observed: 0.214 
- Space Group: P 21 21 2
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 59.923 | α = 90 |
b = 165.341 | β = 90 |
c = 79.112 | γ = 90 |
Software Name | Purpose |
---|---|
d*TREK | data scaling |
d*TREK | data reduction |
MOLREP | phasing |
REFMAC | refinement |
PDB_EXTRACT | data extraction |
CrystalClear | data collection |
Entry History 
Deposition Data
- Released Date: 2013-09-04  Deposition Author(s): Gao, Y., Honzatko, R.B.
Revision History (Full details and data files)
- Version 1.0: 2013-09-04
Type: Initial release - Version 1.1: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Database references, Derived calculations, Structure summary - Version 1.2: 2023-09-13
Changes: Data collection, Database references, Refinement description, Structure summary