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Crystal structure of an immune complex at pH 6.5
4GBX
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System
    Structure Weight: 92815.03
    Molecule: HLA class II histocompatibility antigen, DM alpha chain
    Polymer: 1 Type: protein Length: 203
    Chains: C
    Mutation: D191N
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DMA DMA RING6
    UniProtKB: Protein Feature View | Search PDB | P28067  
    Molecule: HLA class II histocompatibility antigen, DM beta chain
    Polymer: 2 Type: protein Length: 199
    Chains: D
    Mutation: S64C, D110N,
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DMB DMB RING7
    UniProtKB: Protein Feature View | Search PDB | P28068  
    Molecule: HLA class II histocompatibility antigen, DR alpha chain
    Polymer: 3 Type: protein Length: 191
    Chains: A
    Mutation: C90V
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DRA HLA-DRA1
    UniProtKB: Protein Feature View | Search PDB | P01903  
    Molecule: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Polymer: 4 Type: protein Length: 208
    Chains: B
    Mutation: S59C
    Organism: Homo sapiens
    Gene Name: Gene View for HLA-DRB1
    UniProtKB: Protein Feature View | Search PDB | P04229  
    Molecule: synthetic peptide
    Polymer: 5 Type: protein Length: 10
    Chains: E
    Organism: synthetic construct
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Cricetulus griseus  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Cricetulus griseus  
    Polymer: 3
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera frugiperda  
    Polymer: 4
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera frugiperda  
    Polymer: 5
    Scientific Name: Synthetic construct (synthetic construct)   Taxonomy    
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    NAG
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    NAG C8 H15 N O6
    N-ACETYL-D-GLUCOSAMINE
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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