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Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone
4EYW
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Transferase/transferase Inhibitor
    Structure Weight: 144388.81
    Molecule: Carnitine O-palmitoyltransferase 2, mitochondrial
    Polymer: 1 Type: protein Length: 634
    Chains: A, B
    EC#: 2.3.1.21   
    Fragment: UNP residues 27-658
    Organism: Rattus norvegicus
    Gene Names: Cpt2 Cpt-2
    UniProtKB: Protein Feature View | Search PDB | P18886  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Rattus norvegicus   Taxonomy   Common Name: Brown rat,rat,rats Expression System: Escherichia coli  
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    L0R
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    L0R C23 H26 N2 O3
    1-[(2R)-2-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)piperidin- 1-yl]-2-phenoxyethanone
    L0R:4EYW
    P6G
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    P6G C12 H26 O7
    HEXAETHYLENE GLYCOL
    P6G:4EYW
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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