Download MendeleyA Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
Li, W., Damme, M., Buessow, K., Grimm, I., Van Den Heuvel, J., Heinz, D.W., Krausze, J.To be published.
4D3Z
The structure of inactive prolegumain from chinese hamster, trigonal space group.
- PDB DOI: https://doi.org/10.2210/pdb4D3Z/pdb
- Classification: HYDROLASE
- Organism(s): Cricetulus griseus
- Mutation(s): No
- Deposited: 2014-10-24 Released: 2016-01-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.233
- R-Value Work: 0.163
- R-Value Observed: 0.167
This is version 2.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PROLEGUMAIN | 408 | Cricetulus griseus | Mutation(s): 0 EC: 3.4.22.34 |  | |
UniProt | |||||
Find proteins for G3I1H5 (Cricetulus griseus) Explore G3I1H5 Go to UniProtKB: G3I1H5 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | G3I1H5 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | B [auth A], C [auth A], D [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
| Modified Residues 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| CSX Query on CSX | A | L-PEPTIDE LINKING | C3 H7 N O3 S |  | CYS |
| SNN Query on SNN | A | L-PEPTIDE LINKING | C4 H6 N2 O2 |  | ASN |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.233
- R-Value Work: 0.163
- R-Value Observed: 0.167
- Space Group: P 32 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 50.81 | α = 90 |
| b = 50.81 | β = 90 |
| c = 253.59 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2016-01-20 Deposition Author(s): Li, W., Heinz, D.W., Krausze, J.
Revision History (Full details and data files)
- Version 1.0: 2016-01-20
Type: Initial release - Version 1.1: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Other, Structure summary - Version 2.0: 2023-11-15
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2023-12-20
Changes: Refinement description
