4YY1

The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013) in complex with human receptor analog 6'SLNLN


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.10 Å
  • R-Value Free: 0.254 
  • R-Value Work: 0.210 
  • R-Value Observed: 0.212 

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This is version 2.0 of the entry. See complete history


Literature

Structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)

Wang, F.Qi, J.Bi, Y.Zhang, W.Wang, M.Wang, M.Liu, J.Yan, J.Shi, Y.Gao, G.F.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
HA1
A, C
325H6N1 subtypeMutation(s): 0 
UniProt
Find proteins for A0A0J9X268 (H6N1 subtype)
Explore A0A0J9X268 
Go to UniProtKB:  A0A0J9X268
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupA0A0J9X268
Sequence Annotations
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  • Reference Sequence
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Entity ID: 2
MoleculeChains Sequence LengthOrganismDetailsImage
HA2
B, D
164H6N1 subtypeMutation(s): 0 
UniProt
Find proteins for A0A0J9X267 (H6N1 subtype)
Explore A0A0J9X267 
Go to UniProtKB:  A0A0J9X267
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupA0A0J9X267
Sequence Annotations
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  • Reference Sequence
Oligosaccharides

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Entity ID: 3
MoleculeChains Length2D Diagram Glycosylation3D Interactions
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
E, G
2N-Glycosylation
Glycosylation Resources
GlyTouCan:  G42666HT
GlyCosmos:  G42666HT
GlyGen:  G42666HT
Entity ID: 4
MoleculeChains Length2D Diagram Glycosylation3D Interactions
N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose
F, H
2N/A
Glycosylation Resources
GlyTouCan:  G63069TR
GlyCosmos:  G63069TR
GlyGen:  G63069TR
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.10 Å
  • R-Value Free: 0.254 
  • R-Value Work: 0.210 
  • R-Value Observed: 0.212 
  • Space Group: P 3
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 97.06α = 90
b = 97.06β = 90
c = 131.649γ = 120
Software Package:
Software NamePurpose
PHENIXrefinement
HKL-2000data processing
PHASERphasing
Cootmodel building
SCALAdata reduction
SCALEPACKdata scaling

Structure Validation

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Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
China Ministry of Science and Technology National 973 ProjectChina2011CB504703
Intramural Special Grant for Influenza Virus Research from the Chinese Academy of SciencesChinaKJZD-EW-L09
Intramural Special Grant for Strategic Priority Research Program of the Chinese Academy of SciencesChinaXDB08020100
National Natural Science Foundation of ChinaChina31402196
China National Grand S&T Special ProjectChina2014ZX10004002

Revision History  (Full details and data files)

  • Version 1.0: 2016-03-23
    Type: Initial release
  • Version 2.0: 2020-07-29
    Type: Remediation
    Reason: Carbohydrate remediation
    Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary