Download MendeleyCrystal structure of Rv3557c/KstR2, a transcriptional repressor involved in cholesterol metabolism in Mycobacterium tuberculosis.
Dawes, S.S., Kendall, S.K., Baker, E.N., Lott, J.S.To be published.
4W1U
Crystal structure of Rv3557c/KstR2, a transcriptional repressor involved in cholesterol metabolism in Mycobacterium tuberculosis
- PDB DOI: https://doi.org/10.2210/pdb4W1U/pdb
- Classification: TRANSCRIPTION
- Organism(s): Mycobacterium tuberculosis H37Rv
- Expression System: Escherichia coli BL21
- Mutation(s): No
- Deposited: 2014-08-13 Released: 2015-07-29
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.88 Å
- R-Value Free: 0.200
- R-Value Work: 0.172
- R-Value Observed: 0.173
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| HTH-type transcriptional repressor KstR2 | 204 | Mycobacterium tuberculosis H37Rv | Mutation(s): 0 Gene Names: kstR2, Rv3557c |  | |
UniProt | |||||
Find proteins for P9WMB9 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WMB9 Go to UniProtKB: P9WMB9 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P9WMB9 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.88 Å
- R-Value Free: 0.200
- R-Value Work: 0.172
- R-Value Observed: 0.173
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 72.356 | α = 90 |
| b = 90.292 | β = 128.21 |
| c = 49.693 | γ = 90 |
| Software Name | Purpose |
|---|---|
| iMOSFLM | data reduction |
| SCALA | data scaling |
| ARP | model building |
| WARP | model building |
| PDB_EXTRACT | data extraction |
| PHASER | phasing |
| PHENIX | refinement |
Entry History
Deposition Data
- Released Date: 2015-07-29 Deposition Author(s): Dawes, S.S., Kendall, S.K., Baker, E.N., Lott, J.S.
Revision History (Full details and data files)
- Version 1.0: 2015-07-29
Type: Initial release - Version 1.1: 2017-11-22
Changes: Derived calculations, Refinement description, Source and taxonomy - Version 1.2: 2023-09-27
Changes: Data collection, Database references, Refinement description
