Download MendeleyCrystal structure of bovine CTLA-4, PSI-NYSGRC-012704
Kumar, P.R., Casadevall, A., Almo, S.C.To be published.
4KKN
Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704
- PDB DOI: https://doi.org/10.2210/pdb4KKN/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Bos taurus
- Expression System: Trichoplusia ni
- Mutation(s): No
- Deposited: 2013-05-06 Released: 2013-06-12
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- R-Value Free: 0.241
- R-Value Work: 0.190
- R-Value Observed: 0.192
wwPDB Validation 3D Report Full Report
This is version 2.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Cytotoxic T-lymphocyte associated protein 4 | 133 | Bos taurus | Mutation(s): 0 Gene Names: CTLA-4, CTLA4 |  | |
UniProt | |||||
Find proteins for Q28090 (Bos taurus) Explore Q28090 Go to UniProtKB: Q28090 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q28090 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Oligosaccharides
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | 2D Diagram | Glycosylation | 3D Interactions |
| alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | B | 4 |  | N-Glycosylation | |
Glycosylation Resources | |||||
GlyTouCan: G81315DD GlyCosmos: G81315DD GlyGen: G81315DD | |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- R-Value Free: 0.241
- R-Value Work: 0.190
- R-Value Observed: 0.192
- Space Group: C 2 2 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 80.875 | α = 90 |
| b = 87.831 | β = 90 |
| c = 52.25 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SCALEPACK | data scaling |
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
| CBASS | data collection |
| DENZO | data reduction |
| HKL-2000 | data scaling |
| PHENIX | phasing |
Entry History
Deposition Data
- Released Date: 2013-06-12 Deposition Author(s): Kumar, P.R., Ahmed, M., Banu, R., Bhosle, R., Bonanno, J., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S.J., Scott Glenn, A., Hammonds, J., Hillerich, B., Khafizov, K., Lafleur, J., Attonito, J., Love, J.D., Patel, H., Patel, R., Seidel, R.D., Smith, B., Stead, M., Toro, R., Casadevall, A., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Revision History (Full details and data files)
- Version 1.0: 2013-06-12
Type: Initial release - Version 1.1: 2017-11-15
Changes: Refinement description - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2023-09-20
Changes: Data collection, Database references, Refinement description, Structure summary
