Download MendeleyCrystal structure of tallysomycin biosynthesis protein TlmII
Chang, C., Bigelow, L., Bearden, J., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A.To be published.
4HVM
Crystal structure of tallysomycin biosynthesis protein TlmII
- PDB DOI: https://doi.org/10.2210/pdb4HVM/pdb
- Classification: BIOSYNTHETIC PROTEIN
- Organism(s): Streptoalloteichus hindustanus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2012-11-06 Released: 2012-11-21
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 Å
- R-Value Free: 0.232
- R-Value Work: 0.182
- R-Value Observed: 0.184
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| TlmII | 493 | Streptoalloteichus hindustanus | Mutation(s): 0 Gene Names: tlmII |  | |
UniProt | |||||
Find proteins for A4KUC0 (Streptoalloteichus hindustanus) Explore A4KUC0 Go to UniProtKB: A4KUC0 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A4KUC0 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | E [auth A], F [auth A], G [auth B], H [auth D] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A, B, C, D | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 Å
- R-Value Free: 0.232
- R-Value Work: 0.182
- R-Value Observed: 0.184
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 123.799 | α = 90 |
| b = 128.015 | β = 90 |
| c = 129.307 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SBC-Collect | data collection |
| HKL-3000 | phasing |
| MLPHARE | phasing |
| DM | model building |
| SHELXDE | phasing |
| RESOLVE | model building |
| ARP/wARP | model building |
| COO | model building |
| PHENIX | refinement |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
| DM | phasing |
| RESOLVE | phasing |
| COO | phasing |
Entry History
Deposition Data
- Released Date: 2012-11-21 Deposition Author(s): Chang, C., Bigelow, L., Bearden, J., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Revision History (Full details and data files)
- Version 1.0: 2012-11-21
Type: Initial release - Version 1.1: 2013-09-18
Changes: Structure summary - Version 1.2: 2014-04-16
Changes: Experimental preparation
