Download MendeleyCrystal structure of N26_i1 Fab, an ADCC mediating anti-HIV-1 antibody.
Tolbert, W.D., Wu, X., Pazgier, M.To be published.
4FZE
Crystal structure of N26_i1 Fab, an ADCC mediating anti-HIV-1 antibody.
- PDB DOI: https://doi.org/10.2210/pdb4FZE/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Homo sapiens
- Expression System: Homo sapiens
- Mutation(s): No
- Deposited: 2012-07-06 Released: 2013-07-10
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.245
- R-Value Work: 0.186
- R-Value Observed: 0.191
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| N26_i1 Fab light chain | A [auth L] | 212 | Homo sapiens | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| N26_i1 Fab heavy chain | B [auth H] | 232 | Homo sapiens | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.245
- R-Value Work: 0.186
- R-Value Observed: 0.191
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 95.636 | α = 90 |
| b = 124.452 | β = 97.4 |
| c = 41.433 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| PHASER | phasing |
| CNS | refinement |
| REFMAC | refinement |
| HKL-2000 | data collection |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2013-07-10 Deposition Author(s): Tolbert, W.D., Wu, X., Pazgier, M.
Revision History (Full details and data files)
- Version 1.0: 2013-07-10
Type: Initial release - Version 1.1: 2017-11-15
Changes: Refinement description - Version 1.2: 2019-07-17
Changes: Data collection, Refinement description - Version 1.3: 2021-05-19
Changes: Source and taxonomy - Version 1.4: 2023-09-13
Changes: Data collection, Database references, Refinement description
