4FZ1
Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at high pH
- PDB DOI: https://doi.org/10.2210/pdb4FZ1/pdb
- Classification: TRANSPORT PROTEIN
- Organism(s): Gallus gallus, Psalmopoeus cambridgei
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Membrane Protein: Yes OPMPDBTMMemProtMDmpstruc
- Deposited: 2012-07-05 Released: 2012-08-01
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.36 Å
- R-Value Free: 0.281
- R-Value Work: 0.216
- R-Value Observed: 0.223
This is version 1.2 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Acid-sensing ion channel 1 | 450 | Gallus gallus | Mutation(s): 0 Gene Names: ASIC1, ACCN2 Membrane Entity: Yes |  | |
UniProt | |||||
Find proteins for Q1XA76 (Gallus gallus) Explore Q1XA76 Go to UniProtKB: Q1XA76 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q1XA76 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Pi-theraphotoxin-Pc1a | B [auth D] | 40 | Psalmopoeus cambridgei | Mutation(s): 0 |  |
UniProt | |||||
Find proteins for P60514 (Psalmopoeus cambridgei) Explore P60514 Go to UniProtKB: P60514 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P60514 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | C [auth A], D [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.36 Å
- R-Value Free: 0.281
- R-Value Work: 0.216
- R-Value Observed: 0.223
- Space Group: H 3
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 131.52 | α = 90 |
| b = 131.52 | β = 90 |
| c = 129.92 | γ = 120 |
| Software Name | Purpose |
|---|---|
| ADSC | data collection |
| PHASER | phasing |
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2012-08-01 Deposition Author(s): Baconguis, I., Gouaux, E.
Revision History (Full details and data files)
- Version 1.0: 2012-08-01
Type: Initial release - Version 1.1: 2012-10-03
Changes: Database references - Version 1.2: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Structure summary
