Download MendeleyCrystal structure of Thymidylate Kinase from Staphylococcus aureus in apo-form
Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Jedrzejczak, R., Babnigg, G., Rubin, E., Sacchettini, J., Joachimiak, A., Anderson, W.F.To be published.
4F4I
Crystal structure of Thymidylate Kinase from Staphylococcus aureus in apo-form
- PDB DOI: https://doi.org/10.2210/pdb4F4I/pdb
- Classification: TRANSFERASE
- Organism(s): Staphylococcus aureus subsp. aureus Mu50
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2012-05-10 Released: 2012-05-23
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.45 Å
- R-Value Free: 0.242
- R-Value Work: 0.194
- R-Value Observed: 0.196
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Thymidylate kinase | 229 | Staphylococcus aureus subsp. aureus Mu50 | Mutation(s): 0 Gene Names: tmk, SAV0482 EC: 2.7.4.9 |  | |
UniProt | |||||
Find proteins for P65248 (Staphylococcus aureus (strain Mu50 / ATCC 700699)) Explore P65248 Go to UniProtKB: P65248 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P65248 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.45 Å
- R-Value Free: 0.242
- R-Value Work: 0.194
- R-Value Observed: 0.196
- Space Group: P 1 21 1
- Diffraction Data: https://doi.org/10.18430/M34F4I
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 46.099 | α = 90 |
| b = 91.022 | β = 104.47 |
| c = 47.498 | γ = 90 |
| Software Name | Purpose |
|---|---|
| Blu-Ice | data collection |
| PHASER | phasing |
| REFMAC | refinement |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
Entry History
Deposition Data
- Released Date: 2012-05-23 Deposition Author(s): Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Jedrzejczak, R., Babnigg, G., Rubin, E., Sacchettini, J., Joachimiak, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)
Revision History (Full details and data files)
- Version 1.0: 2012-05-23
Type: Initial release - Version 1.1: 2012-10-10
Changes: Structure summary - Version 1.2: 2017-11-15
Changes: Refinement description - Version 1.3: 2017-11-29
Changes: Database references - Version 1.4: 2023-09-13
Changes: Data collection, Database references, Refinement description
