4CQY
H5 (tyTy) Del133/Ile155Thr Mutant Haemagglutinin in Complex with Avian Receptor Analogue LSTa
- PDB DOI: https://doi.org/10.2210/pdb4CQY/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Influenza A virus (A/turkey/Turkey/1/2005(H5N1))
- Expression System: Spodoptera frugiperda
- Mutation(s): Yes
- Deposited: 2014-02-21 Released: 2014-05-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.05 Å
- R-Value Free: 0.227
- R-Value Work: 0.193
- R-Value Observed: 0.194
This is version 2.1 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| HAEMAGGLUTININ HA1 | 327 | Influenza A virus (A/turkey/Turkey/1/2005(H5N1)) | Mutation(s): 1 |  | |
UniProt | |||||
Find proteins for Q207Z6 (Influenza A virus) Explore Q207Z6 Go to UniProtKB: Q207Z6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q207Z6 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| HAEMAGGLUTININ HA2 | 166 | Influenza A virus (A/turkey/Turkey/1/2005(H5N1)) | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for Q207Z6 (Influenza A virus) Explore Q207Z6 Go to UniProtKB: Q207Z6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q207Z6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Oligosaccharides
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | J [auth A] K [auth A] L [auth A] M [auth C] N [auth C] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
| PO4 Query on PO4 | P [auth C], T [auth E] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.05 Å
- R-Value Free: 0.227
- R-Value Work: 0.193
- R-Value Observed: 0.194
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 89 | α = 90 |
| b = 116.35 | β = 91.69 |
| c = 101.84 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| xia2 | data reduction |
| SCALA | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2014-05-28 Deposition Author(s): Xiong, X., Xiao, H., Martin, S.R., Coombs, P.J., Liu, J., Collins, P.J., Vachieri, S.G., Walker, P.A., Lin, Y.P., McCauley, J.W., Gamblin, S.J., Skehel, J.J.
Revision History (Full details and data files)
- Version 1.0: 2014-05-28
Type: Initial release - Version 1.1: 2014-06-11
Changes: Database references - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Atomic model, Data collection, Derived calculations, Other, Structure summary - Version 2.1: 2023-12-20
Changes: Data collection, Database references, Refinement description, Structure summary
