3ZYQ

Crystal structure of the tandem VHS and FYVE domains of Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS-Hrs) at 1.48 A resolution

Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.48 Å
  • R-Value Free: 0.215 
  • R-Value Work: 0.164 
  • R-Value Observed: 0.167 

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This is version 1.1 of the entry. See complete history. 


Literature

Crystal Structure of the Tandem Vhs and Fyve Domains of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) at 1.48 A Resolution

Muniz, J.R.C., Ayinampudi, V., Shrestha, L., Krojer, T., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bullock, A.

To be published.

Macromolecules
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Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE226Homo sapiensMutation(s): 0 
UniProt & NIH Common Fund Data Resources
Find proteins for O14964 (Homo sapiens)
Explore O14964 
Go to UniProtKB:  O14964
PHAROS:  O14964
GTEx:  ENSG00000185359 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupO14964
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.48 Å
  • R-Value Free: 0.215 
  • R-Value Work: 0.164 
  • R-Value Observed: 0.167 
  • Space Group: I 1 2 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 38.256α = 90
b = 34.346β = 90
c = 170.533γ = 90
Software Package:
Software NamePurpose
REFMACrefinement
MOSFLMdata reduction
SCALEPACKdata scaling
PHASERphasing

Structure Validation

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Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2011-09-07
    Type: Initial release
  • Version 1.1: 2018-01-24
    Changes: Database references