POP-OUT | CLOSE
 
Structure of E.coli rhomboid protease GlpG in complex with monobactam L62
3ZMH
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Hydrolase
    Structure Weight: 22773.22
    Molecule: RHOMBOID PROTEASE GLPG
    Polymer: 1 Type: protein Length: 180
    Chains: A
    EC#: 3.4.21.105   
    Fragment: CORE TM DOMAIN, RESIDUES 91-270
    Details: THE BETA LACTAM RING IS OPENED BY THE NUCLEOPHILIC ATTACK OF S201 ON C2-O1 TO FORM A COVALENT BOND
    Organism: Escherichia coli
    Gene Names: glpG b3424 JW5687
    UniProtKB: Protein Feature View | Search PDB | P09391  
    Membrane Protein:   Source: inferred by homology
    ALPHA-HELICAL
    Intramembrane Proteases
    GlpG rhomboid-family intramembrane protease
     
  •   Structure Validation Hide

    Download full validation report    

     

  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Escherichia coli   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    3ZMI  STRUCTURE OF E.COLI RHOMBOID PROTEASE GLPG IN COMPLEX WITH MONOBACTAM L29 
    3ZMJ  STRUCTURE OF E.COLI RHOMBOID PROTEASE GLPG IN COMPLEX WITH MONOBACTAM L61 
    3ZOT  STRUCTURE OF E.COLI RHOMBOID PROTEASE GLPG IN COMPLEX WITH MONOBACTAM L29 (DATA SET 2) 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    78C
    Search 
    Download 
    78C C15 H17 N O3
    CYCLOPENTYL 2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE
    78C:3ZMH
    BNG
    Search 
    Download 
    BNG C15 H30 O6
    B-NONYLGLUCOSIDE
    CL
    Search 
    Download 
    CL Cl
    CHLORIDE ION
    L62
    Search 
    Download 
    L62 C15 H19 N O3
    cyclopentyl N-[(1R)-3-oxidanylidene-1-phenyl- propyl]carbamate
    L62:3ZMH
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
Downloadable viewers: