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Crystal structure of the SucA domain of Mycobacterium smegmatis KGD, post-decarboxylation intermediate from pyruvate (2-hydroxyethyl-ThDP)
3ZHV
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Oxidoreductase
    Structure Weight: 390804.59
    Molecule: MULTIFUNCTIONAL 2-OXOGLUTARATE METABOLISM ENZYME
    Polymer: 1 Type: protein Length: 868
    Chains: A, B, C, D
    EC#: 2.2.1.5    4.1.1.71   
    Fragment: SUCA-LIKE CATALYTIC DOMAIN, RESIDUES 361-1227
    Organism: Mycobacterium smegmatis
    Gene Names: kgd sucA MSMEG_5049 MSMEI_4922
    UniProtKB: Protein Feature View | Search PDB | A0R2B1  
     
  •   Structure Validation Hide

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  •   Source Hide
    Polymer: 1
    Scientific Name: Mycobacterium smegmatis   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    3ZHQ  CRYSTAL STRUCTURE OF THE H747A MUTANT OF THE SUCA DOMAIN OF MYCOBACTERIUM SMEGMATIS KGD 
    3ZHR  CRYSTAL STRUCTURE OF THE H747A MUTANT OF THE SUCA DOMAIN OF MYCOBACTERIUM SMEGMATIS KGD SHOWING THE ACTIVE SITE LID CLOSED 
    3ZHS  CRYSTAL STRUCTURE OF THE SUCA DOMAIN OF MYCOBACTERIUM SMEGMATIS KGD, FIRST POST-DECARBOXYLATION INTERMEDIATE FROM ALPHA-KETOGLUTARATE 
    3ZHT  CRYSTAL STRUCTURE OF THE SUCA DOMAIN OF MYCOBACTERIUM SMEGMATIS KGD, FIRST POST-DECARBOXYLATION INTERMEDIATE FROM 2-OXOADIPATE 
    3ZHU  CRYSTAL STRUCTURE OF THE SUCA DOMAIN OF MYCOBACTERIUM SMEGMATIS KGD, SECOND POST-DECARBOXYLATION INTERMEDIATE FROM 2-OXOADIPATE 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    CA
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    CA Ca
    CALCIUM ION
    MG
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    MG Mg
    MAGNESIUM ION
    TDW
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    TDW C14 H23 N4 O8 P2 S
    2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]- 4-methyl-2-[(1S)-1-oxidanylethyl]-1,3-thiazol- 3-ium-5-yl]ethyl phosphono hydrogen phosphate
     
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  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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