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Crystal structure of TNFalpha in complex with Adalimumab Fab fragment
3WD5
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System
    Structure Weight: 63935.90
    Molecule: Tumor necrosis factor
    Polymer: 1 Type: protein Length: 157
    Chains: A
    Fragment: Tumor necrosis factor, soluble form
    Organism: Homo sapiens
    Gene Names: Gene View for TNF TNFA TNFSF2
    UniProtKB: Protein Feature View | Search PDB | P01375  
    Molecule: Adalimumab Light Chain
    Polymer: 2 Type: protein Length: 213
    Chains: L
    Organism: Homo sapiens
    Molecule: Adalimumab Heavy Chain
    Polymer: 3 Type: protein Length: 219
    Chains: H
    Organism: Homo sapiens
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Cricetulus griseus  
    Polymer: 3
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Cricetulus griseus  
     
  •   Related PDB Entries Hide
    Identifier Details
    4G3Y  Crystal structure of TNFalpha in complex with Infliximab Fab fragment 
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors
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