Download MendeleyCrystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum
Wernimont, A.K., Dong, A., Hills, T., Amani, M., Perieteanu, A., Lin, Y.H., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R.To be published.
3UOW
Crystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum
- PDB DOI: https://doi.org/10.2210/pdb3UOW/pdb
- Classification: LIGASE
- Organism(s): Plasmodium falciparum 3D7
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2011-11-17 Released: 2011-12-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.72 Å
- R-Value Free: 0.296
- R-Value Work: 0.259
- R-Value Observed: 0.261
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| GMP synthetase | 556 | Plasmodium falciparum 3D7 | Mutation(s): 0 Gene Names: PF10_0123 EC: 6.3.5.2 |  | |
UniProt | |||||
Find proteins for Q8IJR9 (Plasmodium falciparum (isolate 3D7)) Explore Q8IJR9 Go to UniProtKB: Q8IJR9 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8IJR9 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| XMP Query on XMP | C [auth A], E [auth B] | XANTHOSINE-5'-MONOPHOSPHATE C10 H14 N4 O9 P DCTLYFZHFGENCW-UUOKFMHZSA-O |  | ||
| CA Query on CA | D [auth A] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.72 Å
- R-Value Free: 0.296
- R-Value Work: 0.259
- R-Value Observed: 0.261
- Space Group: P 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 43.158 | α = 103.07 |
| b = 67.76 | β = 99.36 |
| c = 99.825 | γ = 94.33 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| macChess | data collection |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| BALBES | phasing |
Entry History
Deposition Data
- Released Date: 2011-12-07 Deposition Author(s): Wernimont, A.K., Dong, A., Hills, T., Amani, M., Perieteanu, A., Lin, Y.H., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2011-12-07
Type: Initial release - Version 1.1: 2017-11-08
Changes: Refinement description - Version 1.2: 2023-09-13
Changes: Data collection, Database references, Derived calculations, Refinement description
