3U7C

crystal structure of the V143I mutant of human carbonic anhydrase II


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 0.93 Å
  • R-Value Free: 0.131 
  • R-Value Observed: 0.105 

wwPDB Validation   3D Report Full Report


This is version 1.1 of the entry. See complete history


Literature

crystal structure of the V143I mutant of human carbonic anhydrase II

West, D.M.Kim, C.U.Tu, C.Gordon, J.Robbins, A.H.Gruner, S.M.Silverman, D.M.Mckenna, R.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Carbonic anhydrase 2260Homo sapiensMutation(s): 1 
Gene Names: CA2
EC: 4.2.1.1
UniProt & NIH Common Fund Data Resources
Find proteins for P00918 (Homo sapiens)
Explore P00918 
Go to UniProtKB:  P00918
PHAROS:  P00918
GTEx:  ENSG00000104267 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP00918
Sequence Annotations
Expand
  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 0.93 Å
  • R-Value Free: 0.131 
  • R-Value Observed: 0.105 
  • Space Group: P 1 21 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 42.296α = 90
b = 41.458β = 104.16
c = 72.083γ = 90
Software Package:
Software NamePurpose
SCALEPACKdata scaling
SHELXrefinement
PDB_EXTRACTdata extraction
ADSCdata collection
DENZOdata reduction
SHELXphasing
SHELXL-97refinement

Structure Validation

View Full Validation Report



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2013-02-13
    Type: Initial release
  • Version 1.1: 2023-09-13
    Changes: Data collection, Database references, Derived calculations, Refinement description