Download MendeleyCrystal structure of Mutant C221D of Carbapenemase CphA from Aeromonas Hydrophila
Delbruck, H., Bebrone, C., Hoffmann, K.M.V., Galleni, M.To be published.
3T9M
Crystal structure of Mutant C221D of Carbapenemase CphA from Aeromonas Hydrophila
- PDB DOI: https://doi.org/10.2210/pdb3T9M/pdb
- Classification: HYDROLASE
- Organism(s): Aeromonas hydrophila
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): Yes
- Deposited: 2011-08-03 Released: 2012-08-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.03 Å
- R-Value Free: 0.223
- R-Value Work: 0.179
- R-Value Observed: 0.181
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Beta-lactamase | 227 | Aeromonas hydrophila | Mutation(s): 1 Gene Names: cphA EC: 3.5.2.6 |  | |
UniProt | |||||
Find proteins for P26918 (Aeromonas hydrophila) Explore P26918 Go to UniProtKB: P26918 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P26918 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ACT Query on ACT | B [auth A], C [auth A] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.03 Å
- R-Value Free: 0.223
- R-Value Work: 0.179
- R-Value Observed: 0.181
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 50.605 | α = 90 |
| b = 64.639 | β = 90 |
| c = 67.14 | γ = 90 |
| Software Name | Purpose |
|---|---|
| MAR345dtb | data collection |
| PHASER | phasing |
| REFMAC | refinement |
| XDS | data reduction |
| SCALA | data scaling |
Entry History
Deposition Data
- Released Date: 2012-08-08 Deposition Author(s): Delbruck, H., Hoffmann, K.M.V.
Revision History (Full details and data files)
- Version 1.0: 2012-08-08
Type: Initial release - Version 1.1: 2023-09-13
Changes: Data collection, Database references, Derived calculations, Refinement description
