3SOV
The structure of a beta propeller domain in complex with peptide S
- PDB DOI: https://doi.org/10.2210/pdb3SOV/pdb
- Classification: Protein Binding/Antagonist
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): Yes 
- Deposited: 2011-06-30 Released: 2011-09-21 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.27 Å
- R-Value Free: 0.180 
- R-Value Work: 0.153 
- R-Value Observed: 0.154 
This is version 1.2 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Low-density lipoprotein receptor-related protein 6 | 318 | Homo sapiens | Mutation(s): 0  Gene Names: LRP6 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O75581 (Homo sapiens) Explore O75581  Go to UniProtKB:  O75581 | |||||
PHAROS:  O75581 GTEx:  ENSG00000070018  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | O75581 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Sclerostin | B [auth Z] | 9 | Homo sapiens | Mutation(s): 2  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9BQB4 (Homo sapiens) Explore Q9BQB4  Go to UniProtKB:  Q9BQB4 | |||||
PHAROS:  Q9BQB4 GTEx:  ENSG00000167941  | |||||
Entity Groups   | |||||
UniProt Group | Q9BQB4 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 3 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | C [auth A], G [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N | |||
FUC Query on FUC | D [auth A], E [auth A], F [auth A], H [auth A] | alpha-L-fucopyranose C6 H12 O5 SHZGCJCMOBCMKK-SXUWKVJYSA-N | |||
GOL Query on GOL | I [auth A], J [auth A], K [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.27 Å
- R-Value Free: 0.180 
- R-Value Work: 0.153 
- R-Value Observed: 0.154 
- Space Group: C 1 2 1
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 103.567 | α = 90 |
b = 47.09 | β = 97.68 |
c = 68.72 | γ = 90 |
Software Name | Purpose |
---|---|
HKL-2000 | data collection |
PHASER | phasing |
PHENIX | refinement |
HKL-2000 | data reduction |
HKL-2000 | data scaling |
Entry History 
Deposition Data
- Released Date: 2011-09-21  Deposition Author(s): Wang, W., Bourhis, E., Zhang, Y., Rouge, L., Wu, Y., Franke, Y., Cochran, A.G.
Revision History (Full details and data files)
- Version 1.0: 2011-09-21
Type: Initial release - Version 1.1: 2013-08-28
Changes: Database references - Version 1.2: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Database references, Derived calculations, Structure summary