Download MendeleyCrystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site
Fedorov, A.A., Fedorov, E.V., Kamat, S., Hitchcock, D., Raushel, F.M., Almo, S.C.To be published.
3R0D
Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site
- PDB DOI: https://doi.org/10.2210/pdb3R0D/pdb
- Classification: HYDROLASE
- Organism(s): Escherichia coli K-12
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2011-03-07 Released: 2012-03-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 Å
- R-Value Free: 0.213
- R-Value Work: 0.195
- R-Value Observed: 0.196
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Cytosine deaminase | 427 | Escherichia coli K-12 | Mutation(s): 0 Gene Names: codA, b0337, JW0328 EC: 3.5.4.1 |  | |
UniProt | |||||
Find proteins for P25524 (Escherichia coli (strain K12)) Explore P25524 Go to UniProtKB: P25524 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P25524 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PXN Query on PXN | B [auth A] | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol C17 H36 O8 GXEZGLLPFFKHGE-FPCVCCKLSA-N |  | ||
| GOL Query on GOL | F [auth A], G [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| ZN Query on ZN | C [auth A], D [auth A], E [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 Å
- R-Value Free: 0.213
- R-Value Work: 0.195
- R-Value Observed: 0.196
- Space Group: H 3 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 145.492 | α = 90 |
| b = 145.492 | β = 90 |
| c = 199.704 | γ = 120 |
| Software Name | Purpose |
|---|---|
| ADSC | data collection |
| BALBES | phasing |
| PHENIX | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
Entry History
Deposition Data
- Released Date: 2012-03-07 Deposition Author(s): Fedorov, A.A., Fedorov, E.V., Kamat, S., Hitchcock, D., Raushel, F.M., Almo, S.C.
Revision History (Full details and data files)
- Version 1.0: 2012-03-07
Type: Initial release - Version 1.1: 2023-09-13
Changes: Data collection, Database references, Derived calculations, Refinement description
