3OOW

Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.75 Å
  • R-Value Free: 0.205 
  • R-Value Work: 0.168 
  • R-Value Observed: 0.170 

wwPDB Validation   3D Report Full Report


This is version 1.4 of the entry. See complete history


Literature

Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.

Filippova, E.V.Wawrzak, Z.Kudritska, M.Edwards, A.Savchenko, A.Anderson, F.W.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Phosphoribosylaminoimidazole carboxylase,catalytic subunit
A, B, C, D, E
A, B, C, D, E, F, G, H
166Francisella tularensis subsp. tularensisMutation(s): 0 
Gene Names: FTT_0896purE
EC: 4.1.1.21
UniProt
Find proteins for Q5NGE9 (Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4))
Explore Q5NGE9 
Go to UniProtKB:  Q5NGE9
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5NGE9
Sequence Annotations
Expand
  • Reference Sequence
Small Molecules
Ligands 4 Unique
IDChains Name / Formula / InChI Key2D Diagram3D Interactions
MPD
Query on MPD

Download Ideal Coordinates CCD File 
DA [auth D],
PA [auth F],
UA [auth G],
X [auth C]
(4S)-2-METHYL-2,4-PENTANEDIOL
C6 H14 O2
SVTBMSDMJJWYQN-YFKPBYRVSA-N
PO4
Query on PO4

Download Ideal Coordinates CCD File 
AB [auth H]
BB [auth H]
EA [auth D]
FA [auth D]
JA [auth E]
AB [auth H],
BB [auth H],
EA [auth D],
FA [auth D],
JA [auth E],
K [auth A],
KA [auth E],
L [auth A],
M [auth A],
Q [auth B],
QA [auth F],
R [auth B],
RA [auth F],
VA [auth G],
WA [auth G],
Y [auth C],
Z [auth C]
PHOSPHATE ION
O4 P
NBIIXXVUZAFLBC-UHFFFAOYSA-K
FMT
Query on FMT

Download Ideal Coordinates CCD File 
AA [auth C]
CB [auth H]
DB [auth H]
GA [auth D]
LA [auth E]
AA [auth C],
CB [auth H],
DB [auth H],
GA [auth D],
LA [auth E],
MA [auth E],
N [auth A],
O [auth A],
S [auth B],
SA [auth F],
T [auth B],
U [auth B],
XA [auth G]
FORMIC ACID
C H2 O2
BDAGIHXWWSANSR-UHFFFAOYSA-N
CL
Query on CL

Download Ideal Coordinates CCD File 
BA [auth D]
CA [auth D]
HA [auth E]
I [auth A]
IA [auth E]
BA [auth D],
CA [auth D],
HA [auth E],
I [auth A],
IA [auth E],
J [auth A],
NA [auth F],
OA [auth F],
P [auth B],
TA [auth G],
V [auth C],
W [auth C],
YA [auth H],
ZA [auth H]
CHLORIDE ION
Cl
VEXZGXHMUGYJMC-UHFFFAOYSA-M
Modified Residues  1 Unique
IDChains TypeFormula2D DiagramParent
MSE
Query on MSE
A, B, C, D, E
A, B, C, D, E, F, G, H
L-PEPTIDE LINKINGC5 H11 N O2 SeMET
Experimental Data & Validation

Experimental Data

Unit Cell:
Length ( Å )Angle ( ˚ )
a = 88.56α = 90
b = 96.3β = 90
c = 128.62γ = 90
Software Package:
Software NamePurpose
Blu-Icedata collection
CCP4model building
MrBUMPphasing
PHENIXmodel building
REFMACrefinement
XSCALEdata scaling
CCP4phasing
PHENIXphasing

Structure Validation

View Full Validation Report



Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2010-09-15
    Type: Initial release
  • Version 1.1: 2011-07-13
    Changes: Version format compliance
  • Version 1.2: 2017-11-08
    Changes: Refinement description
  • Version 1.3: 2023-09-06
    Changes: Data collection, Database references, Derived calculations, Refinement description
  • Version 1.4: 2023-12-06
    Changes: Data collection