Download MendeleyCrystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
Jiang, L., Yuan, C., Wind, T., Andreasen, P.A., Chen, L., Meehan, E.J., Huang, M.To be published.
3M61
Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
- PDB DOI: https://doi.org/10.2210/pdb3M61/pdb
- Classification: Hydrolase/Hydrolase inhibitor
- Organism(s): Homo sapiens
- Expression System: Komagataella pastoris
- Mutation(s): Yes
- Deposited: 2010-03-15 Released: 2010-04-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.68 Å
- R-Value Free: 0.243
- R-Value Work: 0.195
- R-Value Observed: 0.198
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Urokinase-type plasminogen activator | A [auth U] | 253 | Homo sapiens | Mutation(s): 2 Gene Names: PLAU EC: 3.4.21.73 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P00749 (Homo sapiens) Explore P00749 Go to UniProtKB: P00749 | |||||
PHAROS: P00749 GTEx: ENSG00000122861 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00749 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| upain-1 W3A | B [auth P] | 12 | N/A | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.68 Å
- R-Value Free: 0.243
- R-Value Work: 0.195
- R-Value Observed: 0.198
- Space Group: H 3
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 121.705 | α = 90 |
| b = 121.705 | β = 90 |
| c = 43.128 | γ = 120 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data collection |
| AMoRE | phasing |
| REFMAC | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2010-04-07 Deposition Author(s): Jiang, L., Yuan, C., Wind, T., Andreasen, P.A., Chen, L., Meehan, E.J., Huang, M.
Revision History (Full details and data files)
- Version 1.0: 2010-04-07
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2021-11-10
Changes: Database references - Version 1.3: 2023-11-01
Changes: Data collection, Refinement description
