3L7V

Crystal structure of a hypothetical protein smu.1377c from Streptococcus mutans UA159

PDB DOI: https://doi.org/10.2210/pdb3L7V/pdb

Classification: TRANSCRIPTION
Organism(s): Streptococcus mutans UA159
Expression System: Escherichia coli BL21(DE3)
Mutation(s): No

Deposited: 2009-12-29 Released: 2010-07-21
Deposition Author(s): Su, X.-D., Fu, T.-M., Liu, X.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.26 Å
R-Value Free: 0.259
R-Value Work: 0.196
R-Value Observed: 0.199

wwPDB Validation 3D Report Full Report

This is version 1.2 of the entry. See complete history.

Literature

The structure of the hypothetical protein smu.1377c from Streptococcus mutans suggests a role in tRNA modification

Fu, T.-M., Liu, X., Li, L., Su, X.-D.

(2010) Acta Crystallogr Sect F Struct Biol Cryst Commun 66: 771-775

PubMed: 20606270 Search on PubMedSearch on PubMed Central
DOI: https://doi.org/10.1107/S1744309110018944
Primary Citation of Related Structures:
3L7V

PubMed Abstract:
Members of the Sua5_YciO_YrdC protein family are found in both eukaryotes and prokaryotes and possess a conserved alpha/beta twisted open-sheet fold. The Escherichia coli protein YrdC has been shown to be involved in modification of tRNA. The crystal structure of smu.1377c, a hypothetical protein from Streptococcus mutans, has been determined to 2.25 A resolution. From structure analysis and comparison, it is shown that smu.1377c is a member of the Sua5_YciO_YrdC family and that it may play the same role as E. coli YrdC.

Organizational Affiliation

The National Laboratory of Protein Engineering and Plant Genetic Engineering, School of Life Sciences, Peking University, Beijing 100871, People's Republic of China.

Macromolecule Content

Total Structure Weight: 34.41 kDa
Atom Count: 2,127
Modelled Residue Count: 256
Deposited Residue Count: 295
Unique protein chains: 1

Macromolecules

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(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Putative uncharacterized protein smu.1377c	A	295	Streptococcus mutans UA159	Mutation(s): 0 Gene Names: smu.1377c
UniProt
Find proteins for Q8DTG7 (Streptococcus mutans serotype c (strain ATCC 700610 / UA159)) Explore Q8DTG7 Go to UniProtKB: Q8DTG7
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q8DTG7
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
SO4 Query on SO4 Download Ideal Coordinates CCD File SDF format, chain B [auth A] SDF format, chain C [auth A] SDF format, chain D [auth A] SDF format, chain E [auth A] SDF format, chain F [auth A] SDF format, chain G [auth A] SDF format, chain H [auth A] MOL2 format, chain B [auth A] MOL2 format, chain C [auth A] MOL2 format, chain D [auth A] MOL2 format, chain E [auth A] MOL2 format, chain F [auth A] MOL2 format, chain G [auth A] MOL2 format, chain H [auth A]	B [auth A] C [auth A] D [auth A] E [auth A] F [auth A] B [auth A], C [auth A], D [auth A], E [auth A], F [auth A], G [auth A], H [auth A]	SULFATE ION O₄ S QAOWNCQODCNURD-UHFFFAOYSA-L		Interactions Focus chain B [auth A] Focus chain C [auth A] Focus chain D [auth A] Focus chain E [auth A] Focus chain F [auth A] Focus chain G [auth A] Focus chain H [auth A] Interactions & Density Focus chain B [auth A] Focus chain C [auth A] Focus chain D [auth A] Focus chain E [auth A] Focus chain F [auth A] Focus chain G [auth A] Focus chain H [auth A]