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SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
3GBQ
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Complex (signal Transduction/peptide)
    Structure Weight: 9652.06
    Molecule: GRB2
    Polymer: 1 Type: protein Length: 74
    Chains: A
    Fragment: N-TERMINAL SH3 DOMAIN
    Organism: Mus musculus
    Gene Name: Grb2
    UniProtKB: Protein Feature View | Search PDB | Q60631  
    Molecule: SOS-1
    Polymer: 2 Type: protein Length: 12
    Chains: B
    Fragment: RESIDUES 1135 - 1144
    Organism: Mus musculus
    Gene Name: Sos1
    UniProtKB: Protein Feature View | Search PDB | Q62245  
     

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    Polymer: 1
    Scientific Name: Mus musculus   Taxonomy   Common Name: House mouse Expression System: Escherichia coli bl21(de3)  
    Polymer: 2
    Scientific Name: Mus musculus   Taxonomy   Common Name: House mouse  
     
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    Identifier Details
    4GBQ   
     
  •   Modified Residues Hide
    Identifier Formula Parent Type
    ACE
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    ACE C2 H4 O nonPolymer
    NH2
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    NH2 H2 N nonPolymer
     
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Data in orange boxes are gathered from external resources (when available).
 
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  •   Deposition Summary Hide
    Authors:   Wittekind, M.,  Mapelli, C.,  Lee, V.,  Goldfarb, V.,  Friedrichs, M.S.,  Meyers, C.A.,  Mueller, L.

    Deposition:   1996-12-23
    Release:   1997-09-04
    Last Modified (REVDAT):   2009-02-24
     
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    2011-07-13
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  •   Experimental Details Hide
    Method:   SOLUTION NMR
    Exp. Data:
    N/A
    NMR Ensemble
    Conformers Calculated:     200
    Conformers Submitted:     1
    Selection Criteria: n/a
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    Method: SOLUTION NMR