3G5C
Structural and biochemical studies on the ectodomain of human ADAM22
- PDB DOI: https://doi.org/10.2210/pdb3G5C/pdb
- Classification: MEMBRANE PROTEIN
- Organism(s): Homo sapiens
- Expression System: Trichoplusia ni
- Mutation(s): No 
- Deposited: 2009-02-04 Released: 2009-08-18 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.36 Å
- R-Value Free: 0.273 
- R-Value Work: 0.245 
This is version 1.3 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
ADAM 22 | 510 | Homo sapiens | Mutation(s): 0  Gene Names: ADAM22, MDC2 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9P0K1 (Homo sapiens) Explore Q9P0K1  Go to UniProtKB:  Q9P0K1 | |||||
PHAROS:  Q9P0K1 GTEx:  ENSG00000008277  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q9P0K1 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 2 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | C [auth A] D [auth A] E [auth A] I [auth B] J [auth B] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N | |||
CA Query on CA | F [auth A] G [auth A] H [auth A] L [auth B] M [auth B] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.36 Å
- R-Value Free: 0.273 
- R-Value Work: 0.245 
- Space Group: H 3
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 122.09 | α = 90 |
b = 122.09 | β = 90 |
c = 208.69 | γ = 120 |
Software Name | Purpose |
---|---|
MAR345dtb | data collection |
PHASER | phasing |
SOLVE | phasing |
CNS | refinement |
XDS | data reduction |
XDS | data scaling |
CNS | phasing |
Entry History 
Deposition Data
Revision History (Full details and data files)
- Version 1.0: 2009-08-18
Type: Initial release - Version 1.1: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.2: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Database references, Derived calculations, Structure summary - Version 1.3: 2023-09-06
Changes: Data collection, Database references, Refinement description, Structure summary