3FY7

Crystal structure of homo sapiens CLIC3

PDB DOI: https://doi.org/10.2210/pdb3FY7/pdb

Classification: TRANSPORT PROTEIN
Organism(s): Homo sapiens
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2009-01-22 Released: 2009-02-24
Deposition Author(s): Littler, D.R., Curmi, P.M.G., Breit, S.N., Perrakis, A.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 1.95 Å
R-Value Free: 0.287
R-Value Work: 0.231
R-Value Observed: 0.234

wwPDB Validation 3D Report Full Report

This is version 1.2 of the entry. See complete history.

Literature

Structure of human CLIC3 at 2 A resolution

Littler, D.R., Brown, L.J., Breit, S.N., Perrakis, A., Curmi, P.M.G.

(2010) Proteins 78: 1594-1600

PubMed: 20146363 Search on PubMed
DOI: https://doi.org/10.1002/prot.22675
Primary Citation of Related Structures:
3FY7, 3KJY

Organizational Affiliation

Department of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands. dene@phys.unsw.edu.au

Macromolecule Content

Total Structure Weight: 56.84 kDa
Atom Count: 3,711
Modelled Residue Count: 438
Deposited Residue Count: 500
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Chloride intracellular channel protein 3	A, B	250	Homo sapiens	Mutation(s): 0 Gene Names: CLIC3
UniProt & NIH Common Fund Data Resources
Find proteins for O95833 (Homo sapiens) Explore O95833 Go to UniProtKB: O95833
PHAROS: O95833 GTEx: ENSG00000169583
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	O95833
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
SO4 Query on SO4 Download Ideal Coordinates CCD File SDF format, chain C [auth A] SDF format, chain D [auth A] SDF format, chain E [auth B] SDF format, chain F [auth B] MOL2 format, chain C [auth A] MOL2 format, chain D [auth A] MOL2 format, chain E [auth B] MOL2 format, chain F [auth B]	C [auth A], D [auth A], E [auth B], F [auth B]	SULFATE ION O₄ S QAOWNCQODCNURD-UHFFFAOYSA-L		Interactions Focus chain C [auth A] Focus chain D [auth A] Focus chain E [auth B] Focus chain F [auth B] Interactions & Density Focus chain C [auth A] Focus chain D [auth A] Focus chain E [auth B] Focus chain F [auth B]

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 1.95 Å
R-Value Free: 0.287
R-Value Work: 0.231
R-Value Observed: 0.234
Space Group: P 1

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 48.289	α = 69.11
b = 48.673	β = 80.97
c = 60.154	γ = 74.8

Software Package:

Software Name	Purpose
DNA	data collection
AMoRE	phasing
REFMAC	refinement
MOSFLM	data reduction
SCALA	data scaling

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2009-02-24

Deposition Author(s):

Revision History (Full details and data files)

Version 1.0: 2009-02-24
Type: Initial release
Version 1.1: 2011-07-13
Changes: Advisory, Derived calculations, Version format compliance
Version 1.2: 2023-11-01
Changes: Data collection, Database references, Refinement description

Prepare Data

Validate Data

Deposit Data

Help and Resources

3FY7

Crystal structure of homo sapiens CLIC3

Structure of human CLIC3 at 2 A resolution

Entity ID: 1

UniProt & NIH Common Fund Data Resources

Entity Groups

Sequence Annotations

Expand

Experimental Data

Structure Validation

Deposition Data

Revision History (Full details and data files)