3FIA

Crystal structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646e.


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.45 Å
  • R-Value Free: 0.176 
  • R-Value Work: 0.160 
  • R-Value Observed: 0.160 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history


Literature

Crystal structure of the EH 1 domain from human intersectin-1 protein.

Vorobiev, S.M.Chen, Y.Seetharaman, J.Devices, C.Zhao, L.Foote, E.L.Ciccosanti, C.Mao, L.Xiao, R.Acton, T.B.Montelione, G.T.Hunt, J.F.Tong, L.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Intersectin-1121Homo sapiensMutation(s): 2 
Gene Names: ITSNITSN1SH3D1A
UniProt & NIH Common Fund Data Resources
Find proteins for Q15811 (Homo sapiens)
Explore Q15811 
Go to UniProtKB:  Q15811
PHAROS:  Q15811
GTEx:  ENSG00000205726 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ15811
Sequence Annotations
Expand
  • Reference Sequence
Small Molecules
Modified Residues  1 Unique
IDChains TypeFormula2D DiagramParent
MSE
Query on MSE
A
L-PEPTIDE LINKINGC5 H11 N O2 SeMET
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.45 Å
  • R-Value Free: 0.176 
  • R-Value Work: 0.160 
  • R-Value Observed: 0.160 
  • Space Group: C 1 2 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 94.848α = 90
b = 32.021β = 106.45
c = 33.287γ = 90
Software Package:
Software NamePurpose
HKL-2000data collection
SnBphasing
RESOLVEmodel building
REFMACrefinement
HKL-2000data reduction
SCALEPACKdata scaling
RESOLVEphasing

Structure Validation

View Full Validation Report



Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2008-12-30
    Type: Initial release
  • Version 1.1: 2011-07-13
    Changes: Version format compliance
  • Version 1.2: 2017-10-25
    Changes: Author supporting evidence, Refinement description
  • Version 1.3: 2021-10-20
    Changes: Database references, Derived calculations