The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.
Winger, J.A., Derbyshire, E.R., Lamers, M.H., Marletta, M.A., Kuriyan, J.(2008) BMC Struct Biol 8: 42-42
- PubMed: 18842118 
- DOI: https://doi.org/10.1186/1472-6807-8-42
- Primary Citation of Related Structures:  
3ET6 - PubMed Abstract: 
Soluble guanylate cyclases generate cyclic GMP when bound to nitric oxide, thereby linking nitric oxide levels to the control of processes such as vascular homeostasis and neurotransmission. The guanylate cyclase catalytic module, for which no structure has been determined at present, is a class III nucleotide cyclase domain that is also found in mammalian membrane-bound guanylate and adenylate cyclases.
Organizational Affiliation: 
Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. wingerj@berkeley.edu