Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP494, a multitargeted kinase inhibitor
3EN5
Primary Citation
 
 
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Blair, J.A.,  Apsel, B.,  Knight, Z.A.,  Shokat, K.M.

    Deposition:   2008-09-25
    Release:   2008-10-14
    Last Modified (REVDAT):   2011-07-13
     
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    2011-07-13
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    2011-07-13
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  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.66
    R-Value: 0.206 (obs.)
    R-Free: 0.248
    Space Group: P 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 42.30 α = 101.14 
    b = 62.99 β = 92.15 
    c = 74.14 γ = 90.12