Download MendeleyLeishmania major coproporphyrinogen III oxidase with bound ligand
Merritt, E.A., Le Trong, I., Larson, E.T., Shibata, S., Zhang, Z., Anderson, L., Ross, J., Verlinde, C.L.M.J., Buckner, F.S., Van Voorhis, W.C., Hol, G.J.W., Fan, E.To be published.
3DWR
Leishmania major coproporphyrinogen III oxidase with bound ligand
- PDB DOI: https://doi.org/10.2210/pdb3DWR/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Leishmania major
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2008-07-22 Released: 2008-09-09
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 Å
- R-Value Free: 0.186
- R-Value Work: 0.163
- R-Value Observed: 0.164
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Coproporphyrinogen III oxidase | 309 | Leishmania major | Mutation(s): 0 Gene Names: LMAJ006828, LmjF06.1270 EC: 1.3.3.3 |  | |
UniProt | |||||
Find proteins for P84155 (Leishmania major) Explore P84155 Go to UniProtKB: P84155 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P84155 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 0PA Query on 0PA | G [auth A] H [auth A] I [auth A] K [auth B] L [auth B] | cyclopentylacetic acid C7 H12 O2 YVHAIVPPUIZFBA-UHFFFAOYSA-N |  | ||
| ACT Query on ACT | C [auth A], D [auth A], E [auth A], F [auth A], J [auth B] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 Å
- R-Value Free: 0.186
- R-Value Work: 0.163
- R-Value Observed: 0.164
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 75.487 | α = 90 |
| b = 48.06 | β = 90.06 |
| c = 84.442 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
Entry History
Deposition Data
- Released Date: 2008-09-09 Deposition Author(s): Le Trong, I., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Revision History (Full details and data files)
- Version 1.0: 2008-09-09
Type: Initial release - Version 1.1: 2011-07-13
Changes: Advisory, Version format compliance - Version 1.2: 2017-10-25
Changes: Refinement description - Version 1.3: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
